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Up to nine percent of the population suffer from Restless Legs Syndrome (RLS). RLS is a neurological disorder which is characterised by creepy, crawly sensations in the legs and an unpleasant spontaneous leg movement. Symptoms often appear during rest primarily occuring in the evening and at night preventing restful sleep. This can lead to daytime tiredness. It is suspected that the cause is a disorder of neural metabolism. RLS is a chronic and slowly progressing disease that occurs approximately as frequently as migraines or diabetes. Dopamine agonists are thought to be an efficacious treatment option.
Restless Legs Syndrome (RLS) – also thought to be caused by abnormal dopamine activity – is also starting to be treated with dopamine-like drugs. These relieve the strong urge to move the legs that people with RLS experience when they have to sit or lie down for long periods, such as in bed or on long journeys.